Azumanga Daioh is about high school life through the eyes of six girls with unusual personalities: Chiyo (the 10-year-old genius), Osaka (the resident airhead), Sakaki (the shy one prone to cat bites), Tomo (the loose cannon), Yomi (the short-tempered one) and Kagura (the resident jock).
Based on the four-panel comic strip that follows the lives of a group of high school students and teachers, this anime features a compilation of comedic vignettes during a typical day in class over the course of three years.